Publikationen

Publikationen

(2009) Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers.

Antoniou, A.C., O.M. Sinilnikova, L. McGuffog, S. Healey, H. Nevanlinna, T. Heikkinen, J. Simard, A.B. Spurdle, J. Beesley, X. Chen, C. Kathleen Cuningham Foundation Consortium for Research into Familial Breast, S.L. Neuhausen, Y.C. Ding, F.J. Couch, X. Wang, Z. Fredericksen, P. Peterlongo, B. Peissel, B. Bonanni, A. Viel, L. Bernard, P. Radice, C.I. Szabo, L. Foretova, M. Zikan, K. Claes, M.H. Greene, P.L. Mai, G. Rennert, F. Lejbkowicz, I.L. Andrulis, H. Ozcelik, G. Glendon, Ocgn, A.M. Gerdes, M. Thomassen, L. Sunde, M.A. Caligo, Y. Laitman, T. Kontorovich, S. Cohen, B. Kaufman, E. Dagan, R.G. Baruch, E. Friedman, K. Harbst, G. Barbany-Bustinza, J. Rantala, H. Ehrencrona, P. Karlsson, S.M. Domchek, K.L. Nathanson, A. Osorio, I. Blanco, A. Lasa, J. Benitez, U. Hamann, F.B. Hogervorst, M.A. Rookus, J.M. Collee, P. Devilee, M.J. Ligtenberg, R.B. van der Luijt, C.M. Aalfs, Q. Waisfisz, J. Wijnen, C.E. van Roozendaal, Hebon, S. Peock, M. Cook, D. Frost, C. Oliver, R. Platte, D.G. Evans, F. Lalloo, R. Eeles, L. Izatt, R. Davidson, C. Chu, D. Eccles, T. Cole, S. Hodgson, Embrace, A.K. Godwin, D. Stoppa-Lyonnet, B. Buecher, M. Leone, B. Bressac-de Paillerets, A. Remenieras, O. Caron, G.M. Lenoir, N. Sevenet, M. Longy, S.F. Ferrer, F. Prieur, Gemo, D. Goldgar, A. Miron, E.M. John, S.S. Buys, M.B. Daly, J.L. Hopper, M.B. Terry, Y. Yassin, R. Breast Cancer Family, C. Singer, D. Gschwantler-Kaulich, C. Staudigl, T.O. Hansen, R.B. Barkardottir, T. Kirchhoff, P. Pal, K. Kosarin, K. Offit, M. Piedmonte, G.C. Rodriguez, K. Wakeley, J.F. Boggess, J. Basil, P.E. Schwartz, S.V. Blank, A.E. Toland, M. Montagna, C. Casella, E.N. Imyanitov, A. Allavena, R.K. Schmutzler, B. Versmold, C. Engel, A. Meindl, N. Ditsch, N. Arnold, D. Niederacher, H. Deissler, B. Fiebig, C. Suttner, I. Schonbuchner, D. Gadzicki, T. Caldes, M. de la Hoya, K.A. Pooley, D.F. Easton, G. Chenevix-Trench and Cimba. Hum Mol Genet, 18(22): p. 4442-56.

(2009) Association of ESR1 gene tagging SNPs with breast cancer risk.

Dunning, A.M., C.S. Healey, C. Baynes, A.T. Maia, S. Scollen, A. Vega, R. Rodriguez, N.L. Barbosa-Morais, B.A. Ponder, Search, Y.L. Low, S. Bingham, Epic, C.A. Haiman, L. Le Marchand, Mec, A. Broeks, M.K. Schmidt, Abcs, J. Hopper, M. Southey, Abcfs, M.W. Beckmann, P.A. Fasching, Bbcc, J. Peto, N. Johnson, Bbcs, S.E. Bojesen, B. Nordestgaard, Cgps, R.L. Milne, J. Benitez, B.C.S. Cnio, U. Hamann, Y. Ko, Genica, R.K. Schmutzler, B. Burwinkel, H. Gc, P. Schurmann, T. Dork, Habcs, T. Heikkinen, H. Nevanlinna, Hebcs, A. Lindblom, S. Margolin, Karbac, A. Mannermaa, V.M. Kosma, Kbcs, X. Chen, A. Spurdle, kConFab, A.M.G. the, J. Change-Claude, D. Flesch-Janys, Marie, F.J. Couch, J.E. Olson, M. for, G. Severi, L. Baglietto, Mccs, A.L. Borresen-Dale, V. Kristensen, Nbcs, D.J. Hunter, S.E. Hankinson, Nhs, P. Devilee, M. Vreeswijk, Origo, J. Lissowska, L. Brinton, Pbcs, J. Liu, P. Hall, Sasbac, D. Kang, K.Y. Yoo, Sebcs, C.Y. Shen, J.C. Yu, Twbcs, H. Anton-Culver, A. Ziogoas, Ucibcs, A. Sigurdson, J. Struewing, Usrts, D.F. Easton, M. Garcia-Closas, M.K. Humphreys, J. Morrison, P.D. Pharoah, K.A. Pooley, G. Chenevix-Trench, and Bcac. Hum Mol Genet, 18(6): p. 1131-9.

(2009) Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium.

Gaudet, M.M., R.L. Milne, A. Cox, N.J. Camp, E.L. Goode, M.K. Humphreys, A.M. Dunning, J. Morrison, G.G. Giles, G. Severi, L. Baglietto, D.R. English, F.J. Couch, J.E. Olson, X. Wang, J. Chang-Claude, D. Flesch-Janys, S. Abbas, R. Salazar, A. Mannermaa, V. Kataja, V.M. Kosma, A. Lindblom, S. Margolin, T. Heikkinen, K. Kampjarvi, K. Aaltonen, H. Nevanlinna, N. Bogdanova, I. Coinac, P. Schurmann, T. Dork, C.R. Bartram, R.K. Schmutzler, S. Tchatchou, B. Burwinkel, H. Brauch, D. Torres, U. Hamann, C. Justenhoven, G. Ribas, J.I. Arias, J. Benitez, S.E. Bojesen, B.G. Nordestgaard, H.L. Flyger, J. Peto, O. Fletcher, N. Johnson, I. Dos Santos Silva, P.A. Fasching, M.W. Beckmann, R. Strick, A.B. Ekici, A. Broeks, M.K. Schmidt, F.E. van Leeuwen, L.J. Van't Veer, M.C. Southey, J.L. Hopper, C. Apicella, C.A. Haiman, B.E. Henderson, L. Le Marchand, L.N. Kolonel, V. Kristensen, G. Grenaker Alnaes, D.J. Hunter, P. Kraft, D.G. Cox, S.E. Hankinson, C. Seynaeve, M.P. Vreeswijk, R.A. Tollenaar, P. Devilee, S. Chanock, J. Lissowska, L. Brinton, B. Peplonska, K. Czene, P. Hall, Y. Li, J. Liu, S. Balasubramanian, S. Rafii, M.W. Reed, K.A. Pooley, D. Conroy, C. Baynes, D. Kang, K.Y. Yoo, D.Y. Noh, S.H. Ahn, C.Y. Shen, H.C. Wang, J.C. Yu, P.E. Wu, H. Anton-Culver, A. Ziogoas, K. Egan, P. Newcomb, L. Titus-Ernstoff, A. Trentham Dietz, A.J. Sigurdson, B.H. Alexander, P. Bhatti, K. Allen-Brady, L.A. Cannon-Albright, J. Wong, G. Australian Ovarian Cancer Study, G. Chenevix-Trench, A.B. Spurdle, J. Beesley, P.D. Pharoah, D.F. Easton, M. Garcia-Closas and C. Breast Cancer Association. Cancer Epidemiol Biomarkers Prev, 18(5): p. 1610-6.

(2009) Association of hormone receptor status with grading, age of onset, and tumor size in BRCA1-associated breast cancer.

Graeser, M., K. Bosse, M. Brosig, C. Engel, R.K. Schmutzler, B. German Consortium for Hereditary, and C. Ovarian. Virchows Arch, 454(5): p. 519-24.

(2009) Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Graeser, M.K., C. Engel, K. Rhiem, D. Gadzicki, U. Bick, K. Kast, U.G. Froster, B. Schlehe, A. Bechtold, N. Arnold, S. Preisler-Adams, C. Nestle-Kraemling, M. Zaino, M. Loeffler, M. Kiechle, A. Meindl, D. Varga, and R.K. Schmutzler. J Clin Oncol, 27(35): p. 5887-92.

(2009) Nuclear receptor coregulator SNP discovery and impact on breast cancer risk.

Hartmaier, R.J., S. Tchatchou, A.S. Richter, J. Wang, S.E. McGuire, T.C. Skaar, J.M. Rae, K. Hemminki, C. Sutter, N. Ditsch, P. Bugert, B.H. Weber, D. Niederacher, N. Arnold, R. Varon-Mateeva, B. Wappenschmidt, R.K. Schmutzler, A. Meindl, C.R. Bartram, B. Burwinkel, and S. Oesterreich. BMC Cancer, 9: p. 438.

(2009) Brustrekonstruktion durch Eigengewebe bei familiärer Disposition (BRCA1+2-Trägerinnen).

Heitmann C, S.R., Richter-Heine I, Feller AM. Senologie 3: p. 203-9.

(2009) Risiko für Brust- und Eierstockkrebs: Bedeutung, Beratung, genetische Testung und klinische Empfehlungen zur Prävention.

Kast K, D.W., Schmutzler RK. Der Gynäkologe 42: p. 847-52.

(2009) Identification of brain- and bone-specific breast cancer metastasis genes.

Klein, A., C. Olendrowitz, R. Schmutzler, J. Hampl, P.M. Schlag, N. Maass, N. Arnold, R. Wessel, J. Ramser, A. Meindl, S. Scherneck, and S. Seitz. Cancer Lett, 276(2): p. 212-20.

(2009) Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

Milne, R.L., J. Benitez, H. Nevanlinna, T. Heikkinen, K. Aittomaki, C. Blomqvist, J.I. Arias, M.P. Zamora, B. Burwinkel, C.R. Bartram, A. Meindl, R.K. Schmutzler, A. Cox, I. Brock, G. Elliott, M.W. Reed, M.C. Southey, L. Smith, A.B. Spurdle, J.L. Hopper, F.J. Couch, J.E. Olson, X. Wang, Z. Fredericksen, P. Schurmann, M. Bremer, P. Hillemanns, T. Dork, P. Devilee, C.J. van Asperen, R.A. Tollenaar, C. Seynaeve, P. Hall, K. Czene, J. Liu, Y. Li, S. Ahmed, A.M. Dunning, M. Maranian, P.D. Pharoah, G. Chenevix-Trench, J. Beesley, I. kConFab, A. Group, N.V. Bogdanova, N.N. Antonenkova, I.V. Zalutsky, H. Anton-Culver, A. Ziogas, H. Brauch, C. Justenhoven, Y.D. Ko, S. Haas, P.A. Fasching, R. Strick, A.B. Ekici, M.W. Beckmann, G.G. Giles, G. Severi, L. Baglietto, D.R. English, O. Fletcher, N. Johnson, I. dos Santos Silva, J. Peto, C. Turnbull, S. Hines, A. Renwick, N. Rahman, B.G. Nordestgaard, S.E. Bojesen, H. Flyger, D. Kang, K.Y. Yoo, D.Y. Noh, A. Mannermaa, V. Kataja, V.M. Kosma, M. Garcia-Closas, S. Chanock, J. Lissowska, L.A. Brinton, J. Chang-Claude, S. Wang-Gohrke, C.Y. Shen, H.C. Wang, J.C. Yu, S.T. Chen, M. Bermisheva, T. Nikolaeva, E. Khusnutdinova, M.K. Humphreys, J. Morrison, R. Platte, D.F. Easton, and C. Breast Cancer Association. J Natl Cancer Inst, 101(14): p. 1012-8.

(2009) Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

Osorio, A., R.L. Milne, G. Pita, P. Peterlongo, T. Heikkinen, J. Simard, G. Chenevix-Trench, A.B. Spurdle, J. Beesley, X. Chen, S. Healey, KconFab, S.L. Neuhausen, Y.C. Ding, F.J. Couch, X. Wang, N. Lindor, S. Manoukian, M. Barile, A. Viel, L. Tizzoni, C.I. Szabo, L. Foretova, M. Zikan, K. Claes, M.H. Greene, P. Mai, G. Rennert, F. Lejbkowicz, O. Barnett-Griness, I.L. Andrulis, H. Ozcelik, N. Weerasooriya, Ocgn, A.M. Gerdes, M. Thomassen, D.G. Cruger, M.A. Caligo, E. Friedman, B. Kaufman, Y. Laitman, S. Cohen, T. Kontorovich, R. Gershoni-Baruch, E. Dagan, H. Jernstrom, M.S. Askmalm, B. Arver, B. Malmer, B. Swe, S.M. Domchek, K.L. Nathanson, J. Brunet, Y.C.T. Ramon, D. Yannoukakos, U. Hamann, Hebon, F.B. Hogervorst, S. Verhoef, E.B. Gomez Garcia, J.T. Wijnen, A. van den Ouweland, Embrace, D.F. Easton, S. Peock, M. Cook, C.T. Oliver, D. Frost, C. Luccarini, D.G. Evans, F. Lalloo, R. Eeles, G. Pichert, J. Cook, S. Hodgson, P.J. Morrison, F. Douglas, A.K. Godwin, Gemo, O.M. Sinilnikova, L. Barjhoux, D. Stoppa-Lyonnet, V. Moncoutier, S. Giraud, C. Cassini, L. Olivier-Faivre, F. Revillion, J.P. Peyrat, D. Muller, J.P. Fricker, H.T. Lynch, E.M. John, S. Buys, M. Daly, J.L. Hopper, M.B. Terry, A. Miron, Y. Yassin, D. Goldgar, R. Breast Cancer Family, C.F. Singer, D. Gschwantler-Kaulich, G. Pfeiler, A.C. Spiess, T.V. Hansen, O.T. Johannsson, T. Kirchhoff, K. Offit, K. Kosarin, M. Piedmonte, G.C. Rodriguez, K. Wakeley, J.F. Boggess, J. Basil, P.E. Schwartz, S.V. Blank, A.E. Toland, M. Montagna, C. Casella, E.N. Imyanitov, A. Allavena, R.K. Schmutzler, B. Versmold, C. Engel, A. Meindl, N. Ditsch, N. Arnold, D. Niederacher, H. Deissler, B. Fiebig, R. Varon-Mateeva, D. Schaefer, U.G. Froster, T. Caldes, M. de la Hoya, L. McGuffog, A.C. Antoniou, H. Nevanlinna, P. Radice, J. Benitez and Cmba. Br J Cancer, 101(12): p. 2048-54.

(2009) No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study.

Rebbeck, T.R., A.C. Antoniou, T.C. Llopis, H. Nevanlinna, K. Aittomaki, J. Simard, A.B. Spurdle, KconFab, F.J. Couch, L.H. Pereira, M.H. Greene, I.L. Andrulis, N. Ontario Cancer Genetics, B. Pasche, V. Kaklamani, R. Breast Cancer Family, U. Hamann, C. Szabo, S. Peock, M. Cook, P.A. Harrington, A. Donaldson, A.M. Male, C.A. Gardiner, H. Gregory, L.E. Side, A.C. Robinson, L. Emmerson, I. Ellis, Embrace, J.P. Peyrat, J. Fournier, P. Vennin, C. Adenis, D. Muller, J.P. Fricker, M. Longy, O.M. Sinilnikova, D. Stoppa-Lyonnet, Gemo, R.K. Schmutzler, B. Versmold, C. Engel, A. Meindl, K. Kast, D. Schaefer, U.G. Froster, G. Chenevix-Trench, and D.F. Easton. Breast Cancer Res Treat, 115(1): p. 185-92.

(2009) Platinum sensitivity in a BRCA1 mutation carrier with advanced breast cancer.

Rhiem, K., B. Wappenschmidt, K. Bosse, H. Koppler, A.N. Tutt, and R.K. Schmutzler. Clin Oncol (R Coll Radiol), 21(6): p. 448-50.

RK, S., Hereditary Breast Cancer, in Hereditary Tumors 2009, R.H. Allgayer H, Fulda S Editor. 2009, Wiley-Blackwell

 

(2009) Decreased expression of angiogenesis antagonist EFEMP1 in sporadic breast cancer is caused by aberrant promoter methylation and points to an impact of EFEMP1 as molecular biomarker.

Sadr-Nabavi, A., J. Ramser, J. Volkmann, J. Naehrig, F. Wiesmann, B. Betz, H. Hellebrand, S. Engert, S. Seitz, R. Kreutzfeld, T. Sasaki, N. Arnold, R. Schmutzler, M. Kiechle, D. Niederacher, N. Harbeck, E. Dahl, and A. Meindl. Int J Cancer, 124(7): p. 1727-35.

Das hereditäre Mammakarzinom: Genetik und Prävention.

Schmutzler RK, M.A., in Aktuelle Empfehlungen zur Therapie primärer und fortgeschrittener Mammakarzinome 2009, K. Mamma, Editor. 2009, Zuckschwerdt Verlag.

(2009) A breast cancer risk haplotype in the caspase-8 gene.

Shephard, N.D., R. Abo, S.H. Rigas, B. Frank, W.Y. Lin, I.W. Brock, A. Shippen, S.P. Balasubramanian, M.W. Reed, C.R. Bartram, A. Meindl, R.K. Schmutzler, C. Engel, B. Burwinkel, L.A. Cannon-Albright, K. Allen-Brady, N.J. Camp, and A. Cox. Cancer Res, 69(7): p. 2724-8.

Consortium of Investigators of Modifiers of (2009) The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

Sinilnikova, O.M., A.C. Antoniou, J. Simard, S. Healey, M. Leone, D. Sinnett, A.B. Spurdle, J. Beesley, X. Chen, kConFab, M.H. Greene, J.T. Loud, F. Lejbkowicz, G. Rennert, S. Dishon, I.L. Andrulis, Ocgn, S.M. Domchek, K.L. Nathanson, S. Manoukian, P. Radice, I. Konstantopoulou, I. Blanco, A.L. Laborde, M. Duran, A. Osorio, J. Benitez, U. Hamann, F.B. Hogervorst, T.A. van Os, H.J. Gille, Hebon, S. Peock, M. Cook, C. Luccarini, D.G. Evans, F. Lalloo, R. Eeles, G. Pichert, R. Davidson, T. Cole, J. Cook, J. Paterson, C. Brewer, Embrace, D.J. Hughes, I. Coupier, S. Giraud, F. Coulet, C. Colas, F. Soubrier, E. Rouleau, I. Bieche, R. Lidereau, L. Demange, C. Nogues, H.T. Lynch, Gemo, R.K. Schmutzler, B. Versmold, C. Engel, A. Meindl, N. Arnold, C. Sutter, H. Deissler, D. Schaefer, U.G. Froster, H. Gc, K. Aittomaki, H. Nevanlinna, L. McGuffog, D.F. Easton, G. Chenevix-Trench, D. Stoppa-Lyonnet, and B.. Br J Cancer, 101(8): p. 1456-60.

(2009) A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women.

Tchatchou, S., A. Jung, K. Hemminki, C. Sutter, B. Wappenschmidt, P. Bugert, B.H. Weber, D. Niederacher, N. Arnold, R. Varon-Mateeva, N. Ditsch, A. Meindl, R.K. Schmutzler, C.R. Bartram, and B. Burwinkel. Carcinogenesis, 30(1): p. 59-64.

(2009) Polymorphisms in BRCA2 resulting in aberrant codon-usage and their analysis on familial breast cancer risk.

Yang, R., B. Chen, K. Hemminki, B. Wappenschmidt, C. Engel, C. Sutter, N. Ditsch, B.H. Weber, D. Niederacher, N. Arnold, A. Meindl, C.R. Bartram, R.K. Schmutzler, and B. Burwinkel. Breast Cancer Res Treat, 118(2): p. 407-13.